Micelle Purification in Continuous Flow via Inline Dialysis

Micelle dispersions purification is made available via inline flow dialysis in which micelles are separated from the organic solvent used to dissolve block copolymers micelle formation step. Purification was performed using simple and cost-effective units employing cellulose membranes. The proposed setup allows us remove THF a dispersion within few hours almost entirely looped system, without significantly changing size. found be independent of exact rates only on circulation time through units. system not able reduce concentration solvent, but also water-soluble monomers can removed. Further, integration method into full synthesis line produce encapsulated directly copolymer solutions demonstrated with throughput 1.2 g per hour.